Writing in the journal Stem Cells Translational Medicine , an international research team, led by physician-scientists at University of California San Diego School of Medicine, describe a new method for delivering neural precursor cells (NSCs) to spinal cord injuries in rats, reducing the risk of further injury and boosting the propagation of potentially reparative cells.
In the first national study of its size, researchers at University of California San Diego School of Medicine and UC San Diego Health, Department of Nursing, have found that male and female nurses are at higher risk of suicide than the general population. Results of the longitudinal study were published in the February 3, 2020 online edition of WORLDviews on Evidence Based-Nursing.
Acid reflux drugs that are sometimes recommended to ease stomach problems during cancer treatment may have an unintended side effect: impairment of breast cancer survivors’ memory and concentration.
By figuring out how a common virus hides from the immune system, scientists have identified a potential vaccine to prevent sometimes deadly respiratory infections in humans.
A solar energy material that is remarkably durable and affordable is regrettably also unusable if it barely generates electricity, thus many researchers had abandoned emerging organic solar technologies. But lately, a shift in the underlying chemistry has boosted power output, and a new study has revealed counterintuitive tweaks making the new chemistry successful.
Mice fed a plant-rich diet are less susceptible to gastrointestinal (GI) infection from a pathogen such as the one currently under investigation for a widespread E. coli outbreak tied to romaine lettuce, UT Southwestern researchers report. A strain of E. coli known as EHEC, which causes debilitating and potentially deadly inflammation in the colon with symptoms such as bloody diarrhea and vomiting, is implicated in several foodborne outbreaks worldwide each year.
Deoxyribonucleic acid or DNA encodes information, not only in its sequence but also in its shape. Building upon previous revelatory work, a team of scientists, led by researchers at University of California San Diego, the UC San Diego branch of the Ludwig Institute for Cancer Research, Stanford University and the Howard Hughes Medical Institute, report that in cancer, distinct doughnut-shaped circles of extrachromosomal DNA (ecDNA) are found abundantly in human tumor cells; change how cancer-related oncogenes are expressed; promote aggressive malignant behavior; and play a key role in the ability of tumors to evolve quickly and resist threats, such as chemotherapy, radiation and other treatments.
One of the ways a cancer-causing gene works up enough power to turn a normal cell into a cancer cell is by copying itself over and over, like a Xerox machine. Scientists have long noticed that when cancer-causing genes do that, they also scoop up some extra DNA into their copies. But it has remained unclear whether the additional DNA helps drive cancer or is just along for the ride.
Without occasionally looking under the hood, it’s difficult to predict whether expensive car repairs lie ahead. In a similar way, preventive cardiologists are looking for ways to detect early stage heart disease in people who aren’t currently in treatment.