Using a new computational strategy, researchers at UT Southwestern Medical Center have identified 29 genetic changes that can contribute to rhabdomyosarcoma, an aggressive childhood cancer. The group used Bayesian analysis, a method for statistical inference, in conjunction with screening using CRISPR/Cas9, the much-heralded gene-editing tool, to confirm the statistical predictions.
Want to be a supercentenarian? The chances of reaching the ripe old age of 110 are within reach – if you survive the perilous 90s and make it to 105 when death rates level out, according to a study of extremely old Italians led by UC Berkeley and Sapienza University of Rome.
Good teamwork begins with a cup of coffee for everyone, a new study suggests.
Researchers found that people gave more positive reviews for their group’s performance on a task – and their own contribution – if they drank caffeinated coffee beforehand.
A study from UT Southwestern’s Peter O’Donnell Jr. Brain Institute demonstrates that a bird’s song can be altered – to the syllable – by activating and deactivating a neuronal pathway responsible for helping the brain determine whether a vocalization is performed correctly. Previous research has shown that when a song is performed without perceived error, certain neurons release dopamine to brain areas involved in motor control. The new study shows that by activating and suppressing these neurons, scientists can prompt the birds to change specific syllables in future performances.
Early identification may lead to early, more effective treatment
For the first time, an international team of scientists, led by researchers at University of California San Diego School of Medicine, have determined that an Alzheimer’s disease (AD) polygenic risk score can be used to correctly identify adults with mild cognitive impairment (MCI) who were only in their 50s. MCI is considered a precursor to AD.
Purdue researcher Luis Solorio has helped create a lifelike cancer environment out of polymer to better predict how drugs might stop its course.
A study of four medical marijuana outlets in California suggests that many of their customers don’t fit the profile expected for businesses focused on sick patients.