Principal/Senior Research Associate in Bioanalytical Assay Development

  • Permanent
  • Anywhere

Website Frontera Therapeutics

Frontera Therapeutics

Company : Frontera Therapeutics

Country: United States

Location : Bedford, Massachusetts

Post: Sat, 11 Sep 2021 06:54:39 GMT

Expires: Mon, 11 Oct 2021 23:59:59 GMT

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—————————— Job Description ——————————

Frontera Therapeutics is seeking a Principal/Senior Research Associate to join our Preclinical Development team. The successful candidate will be a creative scientist with demonstrated in-depth knowledge and experience in bioanalytical assay development. This individual will be responsible for the development and execution of bioanalytical methods to support our AAV-based gene therapy programs independently or with the guidance of senior scientist. S/he will be required to design and conduct various bioanalytical assays. S/he will perform data analysis and present the data to the project team. This person will also provide technical support in bioanalytical development for cross-functional project teams within Frontera.

About Frontera

Frontera Therapeutics is an exciting new company looking to become the gene therapy leader for the global markets [China and beyond]. Leveraging our deep scientific expertise and industry know-how, Frontera is developing an innovative platform to make these life changing treatments more affordable and accessible to patients. The company has a rich product pipeline in various stage of development. Backed by proven investors and an experienced leadership team, our aim is to make gene therapy available to everyone in the world.

We are committed to delivering the highest quality product for patients at affordable price, and we are looking for creative problem solvers to join our collaborative and fast-paced team in Boston area. As an early employee, you will have the unique opportunity to impact our culture and values. This is an excellent opportunity for individuals looking to grow and become the next leaders in the field.

Key Duties and Responsibilities include, not limited to, the following:

Independently or with guidance, design, develop, troubleshoot, qualify and implement various bioanalytical assays and provide various bioanalytical assay support for all gene therapy programs.

Conduct routine sample testing to support gene therapy research and development

Participate in departmental and cross functional project teams

Author study reports, SOPs, and assay procedures

Maintain detailed and well-organized documentation with best industry practice

Effectively analyze, summarize and present the data to the project teams

Collaborate with internal cross-functional team members


A B.S or M.S. in Cell and/or Molecular Biology, Biochemistry, Pharmacology, Immunology or related disciplines, with 5-10 years of academia laboratory or industry experience working in a neuroscience, immunology, AAV gene therapy, or bioanalytical laboratory.

Extensive technical and hands-on experience in various bioanalytical assays in different biological matrices (rodent, NHP, human, etc.) for non-GLP/GLP studies

In-depth knowledge and hands-on experience in cell culture and cell-based assays, cell and tissue processing, ELISA, western blot, RT-qPCR, bDNA assay, ddPCR, MSD, and other various platforms

Ability to learn new techniques and perform multiple tasks simultaneously

Proven ability to work independently and to be a good team player in a hands-on laboratory setting

Self-motivated, have pro-active and positive can-do attitude

Attention to details, with strong scientific, organizational and documentation skills

Strong analytical and problem-solving skills

Being willing to work in a fast-paced start-up environment with demonstrated capacity to handle multiple tasks and demands

Experience in AAV gene therapy is a plus

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