Research Associate

Company : LanceSoft Inc

Country: United States

Location : Seattle, Washington

Post: Sat, 30 Jul 2022 18:51:49 GMT

Expires: Sat, 27 Aug 2022 23:59:59 GMT

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—————————— Job Description ——————————

Job Title: Research Associate

Location: Seattle, WA, 98109

Duration: 12 Months

Job Summary:

We are seeking an enthusiastic, self-driven individual to join the Gene Delivery Process & Analytical Development team and support the development of next-generation technologies to enable non-viral delivery for our cell therapy processes. This Research Associate will support execution of analytical methods for nanoparticle characterization, as well as scale-up activities for nanoparticle formulations.

Job Requirements:

Familiarity in separation techniques (HPLC/UPLC, FFF, SEC), electrophoresis techniques (Client, gel electrophoresis), and nanoparticle physicochemical characterization (UV-Vis, DLS, cryo-EM, nucleic acid quantification, fluorescence plate reader assays like Ribogreen, etc.)

Ability to communicate clearly and concisely through oral presentation and technical writing

Independently motivated with ability to multi-task and problem-solve

Familiarity with lipid-based nanoparticle formulation generation and purification with microfluidic mixing instrumentation, spin-filtration, TFF, sterile filtration, and aseptic processing

Familiarity with aseptic mammalian cell culture (preferably with primary cells)

Experience and working knowledge of concepts like statistical analysis and Design-of-Experiments (DOE)

Education And Experience:

Bachelors (BS) or Masters (MS) Degree in Chemistry, Chemical Engineering, Bioengineering, Biochemistry, or related discipline

0-2 (MS) or 2+ (B.S.) years hands-on lab experience

Job Responsibilities:

Design and execute fit-for-purpose analytical methods to characterize nanoparticle formulations

Design and execute experiments to support downstream purification scale-up activities for nanoparticle formulations (i.e., liposomes, LNPs)

Perform data analysis, interpretation, and presentation to the team and relevant stakeholders

Maintain accurate and detailed electronic laboratory notebook (ELN) and documentation of experimental results

Author technical documents including protocols, reports, and contribute to regulatory documents