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Antibody Drug Conjugate Scientist

  • Anywhere

Company :
Affinity Executive Search

Location :
Pittsburgh, Pennsylvania

Expiry Date :
Fri, 18 Jun 2021 23:59:59 GMT

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Description :
My client seeks a highly motivated and innovative scientist with strong technical and collaborative skills to join their Antibody Engineering group. The ideal candidate will focus on the development of antibody drug conjugates (ADC), including optimizing current strategies and developing novel technologies. This person will play a pivotal role in expanding and leading the ADC programs and pipelines through innovative thinking.

The ideal candidate will take on the following tasks:
–develop novel antibody drug conjugation strategies and carry out bio conjugations of linker and payload combinations to antibodies
–develop novel methods to determine the intracellular trafficking of antibody drug conjugates
–establish an pH-dependent antibody platform and develop methods and assays to characterize in vitro and in vivo ADC stability
–lead the development and application of conjugate purification methodology and design, execute, and trouble-shoot experiments with high degree of independence
–manage projects and reports

The ideal candidate will possess the following requirements:
–Ph.D. in Biochemistry, Molecular Biology, etc with experience working with proteins, antibodies, and conjugation technologies
–strong biochemical, analytical and biophysical skills
–exceptional communication, project management & organizational skills