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Associate Director, Computational Chemistry

  • Anywhere

Company :
Affinity Executive Search

Location :
Cambridge, Massachusetts

Expiry Date :
Sun, 25 Apr 2021 23:59:59 GMT

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Description :
My client is expanding and seeks an experienced Computational Chemist to take on the following tasks:

* Liaise with Data Science and Medicinal Chemistry groups to facilitate effective drug discovery and development.
* Partner with Structural Biology, Medicinal Chemistry and all other relevant functions to drive structure-based design for all ongoing drug discovery programs.
* Analyze biochemical and cellular SAR and other relevant data including in vitro ADME and PK.
* Develop and implement computational chemistry methods to triage compound designs and impact decision-making.
* Build close partnerships with all stakeholders to influence overarching discovery strategy.

The ideal candidate will possess the following qualities:

* PhD with 8+ years of experience, including 4+ years in the biotech field.
* Track record of proven impact through the application of computational chemistry approaches including SBDD, homology modeling, molecular dynamics, and quantum mechanics.
* Deep technical expertise with commonly used computational chemistry tools and methods.
* Skilled in cheminformatics approaches including QSAR and machine learning and data analytics.
* Publications and patents that demonstrate a track record of application of computational approaches to solve problems and advance drug discovery.
* Knowledge of ADME principles, multi-parameter compound design and optimization.