Associate Director or Principal Scientist, Stromal Biology

  • Anywhere

Company :
Bristol-Myers Squibb

Location :
Redwood City, California

Expiry Date :
Mon, 16 Nov 2020 23:59:59 GMT

Apply Job :
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Description :
At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The Tumor Microenvironment Thematic Research Center (TME TRC) at Bristol Myers Squibb is focused on developing therapeutic targets at the intersection of tumor, stromal and immune biology with the goal of enhancing responsiveness to immune checkpoint blockade, targeted and cell therapies.Comprised of scientists across multiple disciplines, we are responsible for the biology and translational science required to support drug development from target identification through proof-of-concept (POC) studies in cancer patients.

Position Summary

We are seeking a highly motivated and experienced Associate Director or Principal Scientist with deep oncology drug discovery and development expertise to join the Immunology and Stromal Biology Discovery group within the TME TRC (Redwood City, CA). The individual will lead a dynamic and matrixed research team responsible for supporting all aspects of drug discovery and development. They will work collaboratively with drug discovery, predictive science, translational and clinical teams to advance molecules (large and small) from target identification/validation, drug discovery to an evaluation of POC in patients. The qualified candidate will bring extensive knowledge in immunology and/or stromal biology and drug development, and will have a proven track record in effectively managing, mentoring and developing scientific teams.

Core Responsibilities:

As a group leader, inspire and direct a team of talented scientists focused on delivering novel therapies that modulate immune and stromal biology within the TME

Contribute to shaping and implementing research strategy that delivers an innovative Immunology and Stromal Biology portfolio within the TME TRC

Ensure key programs are aligned with overall research strategies and appropriate activities and resources are prioritized

Comprehend the competitive oncology landscape, including bridging evolving patient need with emerging scientific breakthroughs to enable drug discovery targeting the TME

Leverage subject matter expertise to identify opportunities and sources of portfolio growth (including from internal and external innovation)

Contribute knowledge and expert opinions across functions, locally and globally

Support a culture of rigorous data-driven decision-making that rewards truth-seeking behavior

Recruit and retain top talent critical to continue business success by developing and mentoring individuals and teams


PhD or MD/PhD in cancer biology, immuno-oncology, stromal biology or equivalent advanced biology degree

Eight (8*) to ten (10)+ years of industry experience, with a proven track record in target validation and drug discovery (*Principal Scientist)

Strong background in biologics and/or small molecule drug discovery, including evidence of subject matter expertise through publications in the field

Excellent verbal and written communication skills across all levels both within an organization and with external with the ability to recognize, articulate and accept calculated risks to make informed decisions

Working knowledge of all functional areas of drug development including toxicology, translational biology and early clinical development

Experience in bringing biologic and/or small molecule programs from preclinical research through to IND submission


Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.