logo

Associate Scientist / Senior Research Associate, cGMP Cell Line Development 2 Positions

  • Anywhere

Company :
Fate Therapeutics, Inc.

Location :
San Diego, California

Expiry Date :
Wed, 16 Dec 2020 23:59:59 GMT

Apply Job :
Open Link

Description :
Employer Fate Therapeutics, Inc. Location San Diego, CA, United States Posted Nov 13, 2020 Ref 416HH Discipline Science/R & D, Biotechnology, Research Hotbed Biotech Beach Required Education Associate Degree Position Type Full time You need to sign in or create an account to save Fate’s Cellular Reprogramming and Engineering Department is seeking a skilled and highly motivated cGMP manufacturing associate scientist/senior research associate to participate in cell line development through cellular reprogramming and genetic engineering in compliance with cGXP guidelines to further the development of novel off-the-shelf cellular therapeutics for the treatment of cancer and immune disorders. The successful candidate will play a key role in the advancement of the company’s induced pluripotent stem cell (iPSC) platform. The candidate should have experience in cGMP manufacturing with strong expertise in cell line development and banking. This is a full-time position reporting to a Scientist, Reprogramming, and is located at our corporate headquarters in San Diego, CA. Responsibilities – Draft, execute and document batch records and SOPs with high level of compliance to safety policies, quality system and cGMP guidance – Participate in iPSC line and other cell line development and banking by adhering to established cGMP SOPs and BRs covering, but not limited to: media preparation, cell culture and scale up, genetic engineering and banking – Document manufacturing procedures in compliance with cGDP requirements – Participate in process and product development activities and write research report as needed – Present manufacturing activities and updates during departments meetings Qualifications – BS/MS in cell biology or similar discipline with a minimum of 3 years of experience in cGMP manufacturing – Strong hands-on experience in aseptic processing in ISO 5 BSC and ISO 7 clean rooms and universal precautions for handling human derived materials in BSL-2 containment areas – Knowledge of cGMP regulations and FDA guidance applicable to biologics and cell therapy manufacturing – Hands-on experience in cell therapy cGMP manufacturing is required – Preferred experience in any of the following: o Cell culture and scale up of iPSCs or immune cells o Cryopreservation processes and equipment o Flow cytometry o Genetic engineering – Demonstrated ability to work both independently and in a team-oriented environment – Excellent communication, attention to detail, and time management/organizational skills – Positive outlook and a team-oriented attitude Working Conditions and Physical Requirements – Will require working with cells and cell lines of human origin – Occasional weekend and/or evening hours as necessary – 100% on-site work at corporate headquarters in San Diego, CA The preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time. For consideration send cover letter and resume to: and reference job code 416HH. About Fate Therapeutics, Inc. Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to the development of first- in-class cellular immunotherapies for cancer and immune disorders. The Company has established a leadership position in the clinical development and manufacture of universal, off-the-shelf cell products using its proprietary induced pluripotent stem cell (iPSC) product platform. The Company’s immuno- oncology product candidates include natural killer (NK) cell and T-cell cancer immunotherapies, which are designed to synergize with well-established cancer therapies, including immune checkpoint inhibitors and monoclonal antibodies, and to target tumor-associated antigens with chimeric antigen receptors (CARs). The Company’s immuno-regulatory product candidates include ProTmune, a pharmacologically modulated, donor cell graft that is currently being evaluated in a Phase 2 clinical trial for the prevention of graft-versus-host disease, and a myeloid-derived suppressor cell immunotherapy for promoting immune tolerance in patients with immune disorders. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit . More searches like this Science/R & D jobs in San Diego Biotechnology jobs in San Diego Research jobs in San Diego