Postdoctoral position on immunotoxins

  • Anywhere

Company :
The Ohio State University

Location :
Columbus, Ohio

Expiry Date :
Mon, 26 Apr 2021 23:59:59 GMT

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Description :
Job Details Full-time$48,000 a year3 hours ago Benefits – Health insurance Qualifications – Laboratory experience – Molecular biology – Doctoral degree Full Job Description The application of potent immunotoxins for targeting cancer cells is limited by their high on- and off-target toxicity, severe side effects, and a narrow therapeutic window. The selectivity of targeting can be improved by intein-based toxin reconstitution from two dysfunctional fragments provided their cytoplasmic delivery via independent, selective pathways (Proc Natl Acad Sci U S A. 2020 Sep 8;117(36): 22090-2210). We aim to achieve reliable cytoplasmic reconstitution of functional bacterial toxins from benign fragments in the cytoplasm of cancer cells. We are looking for outstanding, highly motivated and enthusiastic postdoctoral scientists. Extensive expertise in the following areas is desirable: protein expression and purification, cell biology. The initial position is open for 1 year with a possibility of extension. The primary responsibilities of the postdoctoral fellow will be conducting research, analyzing data, writing manuscripts. Efforts to attract funding will be welcomed and supported. To, please provide: 1) a letter explaining your qualifications and interest to this position, 2) a CV or Biosketch, and 3) names and resses of two or more professional references willing to provide letters of recommendation on your behalf. Ohio State University is one of the largest colleges in the US and a vibrant community of researchers and educators. OSU is located in Columbus – the second larger city in the Midwest that offers a welcoming atmosphere, numerous cultural events, amazing restaurants. Life in Columbus is very affordable, summers are warm, springs and falls are beautiful, winters are moderately cold. Job Type: Full-time Pay: $48,000.00 per year Benefits: – Health insurance Schedule: – 8 hour shift Education: – Doctorate (Preferred) Experience: – Molecular Biology: 1 year (Preferred) – Laboratory Experience: 1 year (Preferred) Work Location: – One location Company’s website: – Work Remotely: – No COVID-19 Precaution(s): – Virtual meetings Quick