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Postdoctoral Research Trainee

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Company :
University of North Carolina at Chapel Hill

Location :
Chapel Hill, North Carolina

Expiry Date :
Sun, 25 Apr 2021 23:59:59 GMT

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Description :
Job Details Full-time$54,000 a year1 hour ago Qualifications – RNA isolation – Doctoral degree Full Job Description Position Title Postdoctoral Research Trainee Vacancy ID PDS Department Peds-Gastroenterology – Position Type Postdoctoral Scholar Salary Range $53,760 – $54,000 Full-time/Part-time Full Time If part-time, hours per week FTE 1.0 Proposed Start Date 05/01/2021 Estimated Duration of Appointment 12 Months Posting Open Date 03/24/2021 Posting Close Date Open Until Filled Yes Work Location Chapel Hill, NC Position Summary This position involves conducting research on microbe-host interactions relevant to inflammatory bowel disease. Specifically, our research focuses on mechanistically understanding how the enteric microbiota regulates intestinal epithelial biology, with an emphasis on Paneth cells. Using novel ex vivo and in vivo approaches, including gnotobiotics, the applicant will study how various clinically-relevant microbes differentially regulate Paneth cell biology. The applicant will be required to perform animal experiments independently and will interface with collaborating laboratories and cores to: i) enumerate Paneth cells and analyze antimicrobial peptide production; ii) perform bulk RNA-seq on isolated PCs; and iii) characterize the impact of probiotic species on Paneth cell function in the context of NSAID-induced enteritis. Note: Initial appointment is 12 months; opportunity to renew appointment up to five years max. Educational Requirements Ph.D required. Qualifications and Experience Prior experience with following techniques is preferred: 1) handling mice (e.g. handling and restraint, genotyping, ear tagging, necropsy, biological fluid and tissue collection); and 2) molecular biology techniques (e.g. qRT-PCR, DNA/RNA isolation, Western blots, flow cytometry, histology, immunofluorescence, and tissue and bacterial culture). Equal Opportunity Employer The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran. Special Instructions For information on UNC Postdoctoral Benefits and Services click here Quick Link Special Physical and Mental Requirements Department Contact Name and Title Katrina Mounlavongsy, HR Consultant Department Contact Telephone or Email Postdoctoral Affairs Apply Now