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Principal Scientist

  • Anywhere

Company :
Bristol-Myers Squibb

Location :
San Diego, California

Expiry Date :
Mon, 14 Jun 2021 23:59:59 GMT

Apply Job :
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Description :
At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. Medicinal Chemist Principal Scientist We are seeking exceptionally talented and highly motivated synthetic/medicinal chemists who are passionate about joining our fast-paced medicinal chemistry group in the pursuit of discovering innovative therapies. The successful candidate will co-lead an early drug discovery team and manage matrixed project teams charged with delivering drug candidates. The candidate will be an expert in the field of organic synthesis and have hands on experience with a wide range of modern synthetic transformations. She/he will contribute to programs by setting strategies, priorities, and driving critical path drug discovery objectives. The candidate will have demonstrated an independent ability in designing and executing on synthetic routes to target molecules, demonstrate a hypothesis driven troubleshooting approach and analytical data interpretation. Knowledge in E3 ligase and UPS biology and chemistry a plus as protein homeostasis at BMS is one of the fundamental research engines delivering therapeutics to patients. Not being bound by therapeutic modality creates a very dynamic, exciting and creative environment where the successful chemist will interface with an excellent team of scientists in biology, biochemistry, structural biology, computational biology and translational development. Qualifications – Ph.D. with 4-6 years postgraduate experience. – M.S. degree with 6-9 years or a B. S. degree with 9-12 years of external research experience. – Track record of innovation and impact on programs documented through co-inventorship on issued patents and authorship of publications in peer-reviewed journals (may include both successful advances and smart terminations). – High level of creativity and productivity with strong synthetic problem-solving skills, synthetic methods, and reaction mechanisms are required. – Committed to experimental work skilled in multi-step synthesis, purification, and state-of-the-art techniques for characterization of organic compounds. – Strong skills in gathering, documenting, and analyzing information from competitive sources such as patents and meetings and using this information to guide program strategy. – Experience with supervising associate level scientists to high levels of productivity, whilst improving the skills and knowledge of direct reports through mentorship. – Broad knowledge of the drug discovery and development process. – A naturally collaborative style as necessary to work effectively in a fast-paced, highly integrated team environment. – Highly collaborative, self-motivated, team-oriented individual, with good computer skills. – Excellent written and oral communication skills demonstrated ability to write peer reviewed quality work or invention disclosures for patent applications, and able to present the rationale, key data, issues and accomplishments department wide. Fit with BMS Culture and Values – Diversity, inclusion and integrity – Strong team orientation; highly collaborative – Solutions and results-oriented focus – Hands-on approach; resourceful and open to diverse points of view Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or any part of the recruitment process direct your inquiries to . Visit to access our complete Equal Employment Opportunity statement.