Principal Scientist, Tissue Systems

  • Anywhere

Company :
United Therapeutics

Location :
Manchester, New Hampshire

Expiry Date :
Fri, 06 Nov 2020 23:59:59 GMT

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Description :
The Job Details are as follows:

What we do

United Therapeutics Corporation focuses on the strength of a balanced, value-creating biotechnology model. We are confident in our future thanks to our fundamental attributes, namely our commitment to quality and innovation, the power of our brands, our entrepreneurial culture and our bioinformatics leadership. We also believe that our determination to be responsible citizens having a positive impact on patients, the environment and society will sustain our success in the long term.

We currently have five approved products on the market and a long-term mission of providing an unlimited supply of transplantable organs for those who need them.

Our company was founded by an entrepreneur whose daughter was diagnosed with a life-threatening condition. She sought to find treatment options and a cure for her daughter and patients like her. We are founder-led, and relentless in our pursuit of medicines for life. We continue to research and develop treatments for cardiovascular and pulmonary diseases, pediatric cancers and other orphan diseases.

How youll contribute

Lead scientific projects to develop tissue-based products for the treatment of pulmonary hypertension and other lung diseases.

Establish robust processes to manufacture engineered lung tissue suitable for lung transplant, with a particular focus on scaffold perfusion and cellularization

Establish robust processes for maturing iPSC-derived cells on 3D printed scaffolds for production of tissue engineered lungs

Lead and contribute to ongoing and new project areas as needed to develop autologous lung tissue engineering products

Manage the development and implementation of analytic methods to characterize engineered lung tissues

Ensure laboratory experiments lead to the successful achievement of program objectives

Ensure processes developed and data collected are sufficient to support regulatory filings

Identify and implement new technology, methods, and protocols to complete program objectives and goals

Work with technicians, research associates, scientists, engineers, and other staff to complete program objectives and goals

Participate in selection, purchase, and implementation of laboratory equipment

Develop, write and review laboratory methods and protocols

Perform tech transfer activities from outside collaborators to internal laboratory

Assist in evaluating new technologies for future product development

Author scientific publications and present data at scientific conferences

Author and contribute to IP and regulatory filings

Perform other duties as assigned

For this role you will need

Minimum Qualifications

PhD in biomedical science or related field, with Postdoctoral training in regenerative medicine

8+ years of pharmaceutical or academic research experience

Prior experience and subject matter expertise in Regenerative Medicine and/or Lung tissue engineering (e.g. tissue engineering, decellularization, biomaterials)

Experience with scientific project management

Experience with Aseptic Technique and mammalian cell culture, as well as protein and molecular biology assays and techniques

Experience with bioreactor and organ culture systems

Excellent communication, with advanced written and oral communication skills

Proficiency with MS Office suite (Excel, PowerPoint, Word, Outlook)

Experience with laboratory instrumentation and data software

Ability to travel up to 10% as needed

Preferred Qualifications

Knowledge and experience with lung cell and stem cell biology

Life as a Unitherian

At United Therapeutics, youll realize quickly that it is not an ordinary place to work! When you join our company, you will learn, grow, contribute, have fun, and be challenged… all while making a difference in the lives of our patients.

United Therapeutics Corporation is an Equal Opportunity/Affirmative Action Employer – EOE Minorities / Females / Protected Veterans / Individuals with Disabilities