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RD Associate II Process Development Downstream

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Company :
University of Massachusetts Medical School

Location :
Mattapan, Massachusetts

Expiry Date :
Mon, 08 Mar 2021 23:59:59 GMT

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Description :
Job Details Full-timeEstimated: $53,000 – $77,000 a year4 hours ago Qualifications – Microsoft Excel – Communication skills – Bachelor’s degree Full Job Description Overview: SUMMARY OF POSITION: The Research Associate II, Process Development – Downstream is part of a team charged with the development of downstream processes for monoclonal antibodies (mAb), recombinant proteins and viral vectors. This position will participate in all aspects of downstream process development including but not limited to lysis/primary recovery, clarification, chromatography, and formulation. Responsibilities: MAJOR RESPONSIBILITIES: Develop robust, scalable, purification processes for mAb, recombinant proteins and viral vectors. Apply QbD principles to characterize and establish process parameters. Assist with the analysis of data in Excel and DOE software, and assist in the preparation of data summaries Assist with writing protocols, project summaries and technical reports. Maintain reagent and equipment inventories, orders supplies and cleans laboratory areas. Operate and maintains standard laboratory equipment and departmental specific equipment. Oversee buffer preparation and packing columns. Ensure that timely and accurate documentation is maintained per GLP. Train and supervise lower level personnel on techniques and equipment. Perform itional job-related duties as required. Qualifications: REQUIRED QUALIFICATIONS: Requires a Bachelor’s degree (or higher) in chemical engineering, biochemical/biological engineering, cell/molecular biology, or biochemistry (or related fields) with a minimum 2-4 years of relevant experience. Direct industry experience in developing purification processes for clinical production of monoclonal antibodies and/or viral gene therapy vectors. Demonstrated expertise in execution of purification unit operations typically applied to mAb, recombinant proteins and viral vectors (e.g. chromatography, filtration, TFF, etc.). Proven ability to recognize, troubleshoot, and solve problems. Excellent written and oral communication skills with the ability to build collaborative relationships. Work effectively as a member of a diverse, multidisciplinary team. Show full job description Apply Now