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Research Assistant II

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Company :
Drexel University

Location :
Philadelphia, Pennsylvania

Expiry Date :
Sun, 28 Mar 2021 23:59:59 GMT

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Description :
Job Details Full-timeEstimated: $30,000 – $44,000 a year1 hour ago Qualifications – Western blot – Molecular biology – Research laboratory experience – DNA isolation – Computer hardware – Master’s degree Full Job Description Job no: Work type: Full-Time Location: Center City – Philadelphia, PA Categories: College of Medicine About Drexel Drexel is a comprehensive global research university ranked among the top 100 in the nation. With over 24,000 students, Drexel is one of America’s 15 largest private universities. Drexel is one of Philadelphia’s top 10 private employers, and a major engine for economic development in the region. Drexel has committed to being the nation’s most civically engaged university, with community partnerships integrated into every aspect of service and academics. Job Summary The Chaiken Laboratory at Drexel University seeks a Research Assistant, with strong hands-on experience in protein biochemistry and molecular biology, to support a research program that investigates molecular and structural mechanisms and antagonism of the envelope protein complexes of HIV-1 and SARS-CoV-2, and has recently discovered molecular strategies to irreversibly inactivate Env and functionally kill both the virus and virus-expressing cells. The Research Assistant will integrate into and be part of the Laboratory’s broad-based research environment that encompasses identification of recombinant and synthetic antagonists, and the use of molecular biology, biophysical methods, cell biology and physical virology approaches to drive investigations of structure-based antagonism of the Env in both enveloped viruses and infected cells. The position will include producing and utilizing recombinant proteins and pseudoviruses, and their site-directed mutants, and analyses of their sensitivity to Env inactivators and antagonists using molecular, biophysical, and cell-based functional analyses. Essential Functions Recombinant protein purification (mammalian and bacterial expression, FPLC, affinity purification) Molecular Biology (PCR, cloning, site-directed mutagenesis, DNA isolation) Biochemical analyses (Western blotting, ELISA, SPR biosensor and other molecular binding methods) Tissue culture (cell lines / primary cells) Purification and characterization of recombinant viruses Cellular and virological assays Operation of standard research lab equipment, and computer hardware and software Required Qualifications Master’s Degree, Biochemistry and Molecular Biology, or closely related field Minimum of 1 year laboratory research experience Operation of standard research lab equipment, and computer hardware and software Preferred Qualifications Hands-on experience for essential functions will be preferred. Location Center City, Philadelphia, PA itional Information This position is classified as Exempt with a salary grade of H. For more information regarding Drexel’s Professional Staff salary structure, Special Instructions to the Applicant Please make sure you upload your CV/resume and cover letter when submitting your application. Review of applicants will begin once a suitable candidate pool is identified. Advertised: Feb 23 2021 Eastern Standard Time Applications close: Mar 23 2021 Eastern Daylight Time Show full job description Apply Now