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Research Fellow Genome Editing Technology Development

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Company :
Mass General Physicians Organization(MGPO)

Location :
Boston, Massachusetts

Expiry Date :
Mon, 08 Mar 2021 23:59:59 GMT

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Description :
Employer Name: SpiderID: Location: Boston, Massachusetts Date Posted: 2/4/2021 Wage: Negotiable Category: Law Enforcement/Security/Safety Job Code: -1492 Job Description: The KleinstiverLaboratory ()in the Center for Genomic Medicine at the Massachusetts General Hospital,Harvard Medical School, is seeking highly motivated post-doctoral fellowcandidates. The Kleinstiver Laboratory develops and applies CRISPR genomeediting technologies for biomedical research and the treatment of humandiseases. We utilize protein engineering methods to impart desirable propertiesinto CRISPR nucleases and base editors, and seek to translate novel and optimizedreagents into clinically relevant primary cell types, including T cells andHSCs. The candidate will play an integral role in projects related to genomeediting technology development and applications thereof.. The new hire will beappointed as a Research Fellow at the Massachusetts General Hospital andPost-Doc at the Harvard Medical School. Interestedcandidates should submit their applications directly via email to Dr.Kleinstiver ()and include the following materials: – acomplete CV detailing scientific experience, publications, presentations,mentorship, etc. – adetailed description of the candidate’s research interests, familiarity withgenome editing technologies, and career aspirations. – contactinformation for three (3) references, including a description of the referee’s familiaritywith the candidate. PRINCIPALDUTIES AND RESPONSIBILITIES: The Post-doctoralFellow will become proficient in the following duties (examples, but notlimited to): routine molecular biology (PCR, recombinant DNA cloning, bacterialtransformations, etc.), biochemical techniques, mammalian cell culture,assessment of genome editing technologies in bacteria and mammalian cells, DNAsequencing methods (Sanger and Illumina next-generation sequencing), designingand executing experiments, analyzing and visualizing data, developing andoptimizing genome editing assays, attending seminars and conferences,interacting with collaborators and peers, assisting with routine laboratorytasks, preparing reagents and solutions, recording experimental details andresults in an electronic notebook, time management, communication skills, andpresenting summaries of work or scientific papers in lab meeting and journalclub, respectively. The Post-Doctoralfellow will be situated in the MGH under the guidance and mentorship of Dr. Kleinstiver. SKILLS & COMPETENCIES REQUIRED: Theideal candidate should have received (or expect to receive soon) a Ph.D. in Biology,Biochemistry, Genomics or other closely related fields. Example skills andcompetencies that the candidate should be familiar with include, but are notlimited to: – Strong proficiency in standard molecular biology techniques – Familiarity with genome, epigenetic, and base editing technologies – Experience with mammalian cell culture, including transformed cancer cell lines, primary human T cells, and/or primary human HSCs – Familiarity with Illumina sequencing methods and data analysis – A general interest in the scientific literature and staying informed of new advances – Experience with commonly used bioinformatics tools and databases, and other standard software – Evidence of a strong publication record, including first (or co-first) author of one or more peer-reviewed scientific publications – Excellent English verbal and written communication skills – Able to work both independently and in a team – Experience mentoring and training others – Exceptional organizational skills EDUCATION: Minimum Required: Doctoral Degree Preferred: Doctoral Degree EXPERIENCE: Required:Recent PhD graduate SUPERVISORYRESPONSIBILITY (authority to hire, promote, or terminate): NotApplicable Interestedapplicants should submit their CV and contacts for references to: Dr. BenKleinstiver (). Qualifications EDUCATION: Minimum Required: Doctoral Degree Preferred: Doctoral Degree EXPERIENCE: Required: Recent PhD graduate EEO Statement Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged. Partner’s Healthcare is acting as an Employment Agency in relation to this vacancy. Job Criteria: Start Date: Position Type: Full-Time Permanent Years of Experience Required: Education Required: Overnight Travel: Vacation Time: Contact Information: Contact Name: Partner’s Healthcare Company Type: Company: Mass General Physicians Organization(MGPO) City: State: Zip: