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Scientist 1

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Company :
Bristol-Myers Squibb

Location :
San Diego, California

Expiry Date :
Sat, 05 Dec 2020 23:59:59 GMT

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Description :
At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. Summary Bristol-Myers Squibb is seeking a highly motivated and innovative scientist to join the Protein Engineering group in the Discovery Biotherapeutics Department in San Diego. The successful candidate will support BMSs protein engineering efforts through antibody/protein design, production, and biophysical analysis. Experience with antibody/protein engineering, purification, and characterization is preferred. Experience with protein modeling, bioinformatics, and machine learning would be highly valued. The successful candidate will have the opportunity to participate in cross-functional project teams to discover and optimize antibody-based therapeutics. The ideal candidate will have a track record of taking initiative and will be able to thrive in a highly dynamic and supportive yet independently thinking culture. The candidate should be highly effective and lead from the bench. Excellent time management, a collaborative spirit, organizational skills, and strong written and oral communication skills are essential. Responsibilities will include, but are not limited to, the following: – Antibody/protein engineering and modeling – Purification of antibody and protein-based biologics – Functional assays including SPR, ELISA, and FACS – Data presentations and updates in the project team meetings – Providing technical solutions to anticipated problems Skills/Knowledge preferred: – PhD in protein sciences, biochemistry, or related fields, with 3 or more years of research experience in antibody/protein discovery – Antibody/protein engineering, construct design, and production – Antibody/protein interaction assay development by SPR, ITC, or immunoprecipitation – Familiarity with biophysical techniques, such as x-ray crystallography, isothermal calorimetry, or multi-angle light scattering – Design, plan and execute scientific experiments with minimal supervision – General assay development for hit-to-lead identification and characterization – Ability to organize data into power point slides for presentations at project/departmental meetings – Excellent notebook keeping, and familiarity with data retrieval and input from a database – Excellent troubleshooting abilities Skills/Knowledge in one or more of the following areas are a plus: – Physics-based antibody/protein modeling – Bioinformatic database analysis – Machine learning – Experience with protein display technologies Functional/Scientific/Technical Skills: – Ability to work independently as well as in a multi-discipline team environment – Ability to multi-task and change priorities based on departmental needs – Ability to embrace a culture of continuous learning and improvement and refining technical skills – Take a proactive role in growth and scientific development – Improve own functional area Discretion/Latitude: – Develop strategies – Accountable for success of strategies – Provide input to develop cross-functional policies Creativity and Problem Solving: – Able to anticipate problems at project levels – Recognize risk and propose contingency plans – Anticipate the need for contingencies and develops alternative strategies Teamwork and Influence: – Communicates within the larger organization – Develops constructive relationships across the organization to achieve company and individual goals and take on leadership roles on cross-functional/divisional teams Organizational Impact: – Impact is achieved through leading workgroups and contributing to cross-functional teams Behavioral Competencies: – Champions change and Leads courageously – Networking – Provides directions – Thinks strategically Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.