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Scientist Mammalian Expression

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Company :
Amgen

Location :
Thousand Oaks, California

Expiry Date :
Sun, 13 Dec 2020 23:59:59 GMT

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Description :
Career_CategoryScientificJob_Description The Mammalian Expression group in Biologics Optimization is responsible for the production of large molecule therapeutics from early stage screening through material supply in manufacturability assessments along with pre-clinical studies. The individual should be innovative in developing methodologies that reduce cycle time and improve quality and quantity of large molecule therapeutics from recombinant mammalian expression systems. This is a laboratory focused position in our state-of-the-art facility in Thousand Oaks, California. Responsibilities Scientific and technical expertise in transient and stable mammalian expression is required for this laboratory position. Championing innovative ideas and facilitating the development and implementation of technologies to express and optimize large molecule therapeutics including antibodies and bispecifics. Solving complex technical problems. Working both independently and in cross-functional teams. Basic_Qualifications Doctorate degree OR Master s degree and 3 years of scientific experience OR Bachelor s degree and 5 years of scientific experience Preferred_Qualifications PhD in Cell Biology, Molecular Biology, Biochemistry or Chemical Engineering and two or more years of biotech/pharma industry experience with emphasis on antibody production and host cell engineering using various mammalian expression systems. Strong knowledge and experience of expression strategies for antibodies and bispecifics in CHO and other mammalian expression hosts. Proficiencies in mammalian cell culture, cell line development, cell line engineering, molecular cloning, transcriptomics, genomics, genome editing, next generation sequencing, and biochemical analysis. Strong communication and interpersonal skills, and the ability to work flexibly in a dynamic and collaborative environment. Demonstrated a strong track record of independent critical thinking and scientific achievement in research, exemplified by publications in highly regarded journals, conference presentations or generation of intellectual property. Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people s lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world s leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. Join Us If you’re seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you’ll find it at Amgen. Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.. Show moreShow less