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Senior Associate Scientist (non PhD), In vivo Pharmacology

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Company :
Bristol-Myers Squibb

Location :
Cambridge, Massachusetts

Expiry Date :
Tue, 06 Apr 2021 23:59:59 GMT

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Description :
Senior Associate Scientist (non-PhD), In vivo Pharmacology At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. The new Bristol-Myers Squibb research site in Cambridge’s Kendall Square will help us continue to deliver on our mission, positioning the company and our scientists in the heart of a vibrant ecosystem of world-class science, innovation, and business opportunities. The Mechanisms of Cancer Resistance (MoCR) Thematic Research Center (TRC) at BMS is one of the fundamental research and early development engines delivering oncology therapeutics to patients. The scientists at this state-of-the-art research and development site in Cambridge focus on novel tumor intrinsic targets and pathways for tumors that are refractory to current oncology therapies and implement our discovery platforms across all of our therapeutic areas of focus. We are seeking an In Vivo Pharmacology Senior Associate Scientist to join the Oncology Discovery Pharmacology and In Vivo Biology group within the Mechanisms of Cancer Resistance (MoCR) organization at Bristol-Myers Squibb located in Cambridge, MA. The qualified non-PhD candidate is a highly motivated, interactive, and creative scientist who will conduct experiments utilizing tumor xenograft and genetically engineered mouse models to advance oncology discovery programs into the clinic. The successful candidate will demonstrate clear and professional communication, effectively collaborate with colleagues across a highly matrixed environment, and is capable of executing, analyzing and presenting scientific results. Qualifications + A B.S. with a minimum of 4 years relevant industry or comparable academic experience leveraging in vivo rodent models to explore cancer biology and enable drug discovery is required. + Demonstrated experience independently running and analyzing data from in vivo xenograft tumor efficacy and PK/PD studies is required. + Required in vivo skills include: rodent handling, rodent dosing (IV, IP, SC, and PO routes), cell line implantation, tumor measurements by caliper, and blood/tissue/tumor collection. + Advanced in vivo skills are a plus, including but not limited to surgical experience with orthotopic tumor implantations in mice. + Experienced with ex vivo/in vitro assays including: proficiency in cell culture (required), qPCR, ELISA, or western blot (highly desired). + Proficiency in utilizing software such as Graph Pad, Microsoft office etc. for data analysis and figure generation is required. + Ability to mentor junior scientists and colleagues on best practices in the laboratory would be highly valued. + Attention to detail with excellent organizational and record keeping skills is a requirement. Responsibilities include: + Independently conduct and analyze in vivo mouse or rat studies including, ATD/MTD, anti-tumor efficacy, body weights, and generation of samples from PK/PD studies. + Contribute to the utilization of ELISAs (MSD), qPCR, or WB to monitor relevant biomarkers in harvested tissues + Accurately maintain proper scientific documentation of experiments and associated data in an electronic lab notebook. + Effectively communicate and present summaries of research results to team members. Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Company: Bristol Myers Squibb Req Number: R-en-us Updated: 2021-03-02 00:29:49.082 UTC Location: Cambridge,Massachusetts Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.