logo

Senior Scientific Researcher, Ophthalmology Biomarker Discovery

  • Anywhere

Company :
Roche

Location :
San Francisco, California

Expiry Date :
Fri, 26 Mar 2021 23:59:59 GMT

Apply Job :
Open Link

Description :
Job Details Full-timeEstimated: $110,000 – $150,000 a year5 hours ago Qualifications – Communication skills – Clinical trials – Organizational skills – Research – Biochemistry – Doctoral degree Full Job Description The Biomarker Discovery OMNI department is seeking a motivated, interactive and flexible Senior Scientific Researcher to participate in biomarker discovery and reverse translational work. This role will focus on deep molecular phenotyping of degenerative retinal diseases using leading-edge molecular technology. The successful candidate will use single cell genomics and spatial transcriptomics to identify pathways, targets and biomarkers, and will be expected to make intellectual as well as technical contributions to the team. This position is a rare opportunity to conduct basic research and immediately incorporate those findings into the clinical development of our therapeutic programs. Responsibilities: Assist the team in identifying biomarkers for molecularly targeted therapies in retinal disease. Performing exploratory disease-oriented research utilizing samples and data from human disease cohorts Processing and analyzing clinical trial samples, data analysis and presentation, and contributing to experimental design/planning. Requirements: Ph.D. in Neurobiology, Biochemistry, Molecular Biology, or a related discipline. Research experience in academic or industry setting, preferably 3 or more years. Recent graduates with an outstanding record of achievement are also strongly encouraged to. Demonstrated ability to independently design and conduct experimental procedures and work collaboratively in a fast-paced team environment. Practical experience with scRNA-Seq, ATAC-Seq, spatial transcriptomics and/or advanced microscopy is highly desired. Familiarity with protein biochemistry, Next Generation Sequencing (NGS), basic bioinformatics/biostatistics, in vitro differentiation cultures (2D and 3D), or demonstrated research experience in retinal biology/neurodegenerative diseases will be an advantage. Excellent organizational skills and oral/written communication skills, problem-solving, flexibility, and the ability to integrate detailed analysis into a larger disease-oriented context will be expected. #LI-NN1 Show full job description Apply Now