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Senior Scientist, Analytical Team Lead

  • Anywhere

Company :
Bristol-Myers Squibb

Location :
New Brunswick, New Jersey

Expiry Date :
Sun, 25 Apr 2021 23:59:59 GMT

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Description :
At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science. In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. Position Summary The Analytical Team Lead (ATL) is responsible for leading analytical project teams within Biologics Development. The Analytical Team Lead coordinates all analytical activities, develops the analytical strategy, establishes the analytical development timeline, and manages matrix teams to support overall CMC development. The ATL assures all biologics CMC analytical deliverables are met for 2-3 projects that initiate at clone selection and advance through BLA filing. The ATL will drive deep scientific knowledge of modality attributes that impact on process and product performance. These modalities may include mAbs, fusion proteins, ADCs, cell therapies, Viral and non-Viral Gene Delivery products. The Analytical Team Lead works with a team of analytical scientists to define the analytical strategy, critical quality attributes, and a phase appropriate control strategy. The ATL is responsible for project planning and assures both timeliness and high quality of deliverables. The individual may be required to help design in-vivo studies where necessary to drive knowledge of attribute impact on PK, efficacy, or toxicity. This individual also represents the analytical function in the CMC team(s) and collaborates with partner functions such as discovery, process development, formulation development, quality, regulatory, manufacturing and supply chain. Close partnership with process and formulation team leaders is essential to develop innovative and robust processes and products. Key Responsibilities The Analytical Team Lead will be directly accountable for managing delivery and timeline of analytical development activities at multiple sites within BMS and with external contract manufacturing and testing laboratories. This includes method development, structural and functional characterization, release testing, comparability, stability studies, regulatory filings, and related activities. The ATL will work closely with SMEs and leaders across biologics development groups, to develop the analytical strategy of the programs assigned to this individual. Qualifications & Experience – PhD or MS in analytical science, biochemistry, pharmaceutical sciences, biology, or related discipline, plus at least 2 years of experience in Biologics CMC development – Proven leader with experience in managing matrix teams in a technical environment. Exceptional interpersonal and communication skills. – Knowledge of analytical and biochemical techniques, chromatography, biological function, protein higher order structure, and biologics characterization – Experience resolving analytical technical issues and challenges – Knowledge of biologics CMC development from pre-clinical through clinical to commercialization – Exceptional program management and project management skills and adept at working collaboratively with cross functional teams – Exceptional experience with portfolio management & prioritization, resource modeling, and expertise with different tools like Timeline Maker and Tableau are desirable. – Experience in oversight of contract manufacturing organizations (CMOs)/contract research organizations (CROs) for biologics method development, characterization, technology transfer, manufacture and release Why You Should Apply Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or any part of the recruitment process direct your inquiries to . Visit to access our complete Equal Employment Opportunity statement.