Senior Scientist Biochemical and Cellular Pharmacology

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South San Francisco, California

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Tue, 06 Apr 2021 23:59:59 GMT

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Job Details Full-timeEstimated: $98,000 – $140,000 a year3 hours ago Benefits – Health insurance Qualifications – Analysis skills – Driver’s License – Communication skills – Hazmat Endorsement – Drug discovery – Doctoral degree Full Job Description Job Description Our company’s Research Laboratories in South San Francisco is seeking a highly capable Senior Scientist with a strong background in biochemical/cellular pharmacology, assay development, and screening to join the Quantitative Biosciences department. The individual will work in the laboratory to independently design, execute, and interpret complex in vitro studies to support drug discovery across multiple therapeutic areas. Successful candidates should demonstrate broad scientific knowledge and technical expertise in pharmacology, a strong track record supporting drug discovery research, and the ability to leverage lab automation to improve efficiency and drive innovation. He or she should have excellent analytical and communication skills and can work effectively in a highly collaborative cross-functional team environment. Key responsibilities: Provide biochemical and cellular pharmacology expertise to support drug discovery across multiple therapeutic areas (cardiometabolic, immunology, and oncology) Develop and implement potency, selectivity, and mechanistic assays to characterize diverse targets, molecules, and mechanism of actions, using sophisticated experimental methods Leverage extensive lab automation to improve quality, efficiency, and overall productivity Drive scientific and technical innovations to enhance functional capability and productivity Represent Quantitative Biosciences department in multi-disciplinary project teams to provide robust scientific and technical support Collaborate extensively across the our research laboratories network and with external partners to drive project progression toward milestones Qualifications: Ph.D. in Pharmacology, Biochemistry, Cell Biology or a related scientific discipline, with a minimum of3 years of drug discovery experience in a biotech/pharmaceutical setting Relevant knowledge of mechanistic pharmacology and bioassay development, and strong expertise in SAR support for drug discovery Highly skilled in the design and execution of high-throughput biochemical and cell assays, using a wide range of modern technologies and detection methods Broad knowledge and hands-on experience with automated liquid handling instruments (Multidrop, Bravo, Echo, etc.) and integrated robotic systems for assay operation Proven record of success in leveraging biochemical and cell assays for compound screening, pharmacological characterization, and lead optimization Good working knowledge of cardiometabolic biology, immunology or oncology is a plus Demonstrated ability to work collaboratively in a cross-functional environment to advance drug discovery, with excellent organization and communication skills We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we ‘follow the science’ that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe. Who we are … We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world’s most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world. What we look for … In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth. INVENT. IMPACT. INSPIRE. NOTICE FOR INTERNAL APPLICANTS In accordance with Managers’ Policy – Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior toing for open positions. If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor. US and Puerto Rico Residents Only: If you need an accommodation for the application process please email us at For more information about personal rights under Equal Employment Opportunity, visit: EEOC Poster EEOC GINA Supplement OFCCP EEO Supplement OFCCP Pay Transparency Rule We are an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations. Search Firm Representatives Please Read Carefully Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: Domestic VISA Sponsorship: No Travel Requirements: Flexible Work Arrangements: Shift: Valid Driving License: Hazardous Material(s): Number of Openings: 1 Requisition ID:R Job Information Job ID: Location: South San Francisco, California, United States Position Title: Senior Scientist – Biochemical and Cellular Pharmacology Company Name: Merck Job Function: Other Job Type: Full-Time Show full job description Apply Now