Senior Scientist Next Generation Sequencing – Durham, North Carolina

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Carolina Beach, North Carolina

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Sun, 08 Nov 2020 23:59:59 GMT

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Senior Scientist – Next Generation Sequencing – Durham, North Carolina

About Syngenta
Syngenta is a global leader in agriculture; rooted in science and dedicated to bringing plant potential to life. Each of our 28,000 employees in more than 90 countries work together to solve one of humanity’s most pressing challenges: growing more food with fewer resources. A diverse workforce and an inclusive workplace environment are enablers of our ambition to be the most collaborative and trusted team in agriculture. Our employees reflect the diversity of our customers, the markets where we operate and the communities which we serve. No matter what your position, you will have a vital role in safely feeding the world and taking care of our planet. Join us and help shape the future of agriculture.
At Syngenta, we are working to build the most collaborative and trusted team in agriculture that provides leading seeds innovations to enhance the prosperity of farmers. We are seeking a Sr Scientist in Next Generation Sequencing (NGS) to provide specialist scientific, technical expertise and leadership required to expand our next generation sequencing (NGS) platform. This role will support all activities related to data generation by our NGS pipeline from project design, optimization of library prep protocols, running sequencing instruments, to primary sequencing data analysis and management. Accountabilities:
Apply a combination of theoretical and applied knowledge in order to strategize, guide and lead the delivery NGS-related work programs
Provide high quality practical advice to others by applying broad NGS-related experimental and data analytics work experience and theoretical knowledge
Coordinate and carry out tissue collection and preparation, DNA & RNA extraction, NGS library preparation and sequencing of libraries on in-house sequencing equipment
Provide data analysis and management expertise to NGS applications and support trait research and product
Evaluate new methods and technologies to enable the expansion of next generation sequencing (NGS) platform for higher throughput, lower cost applications (e.g., cheaper library prep, new approaches to DNA concentration normalization, etc.)
Support testing of novel methods for genotyping involving NGS as well as more traditional PCR-based approaches
Provide in-house support for continuing efforts towards rare variant detection using NGS
Be familiar with, and provide appropriate documentation for ensuring the capture of intellectual property
Manage day to day expectations of stakeholders

Ph.D., or a Masters degree with 3+ years of professional experience, in Molecular Biology, Plant Biochemistry, Genomics or related field
A strong understanding of NGS fundamentals and applications, critical factors influencing data quality, and an ability to troubleshoot the sequencing process end to end
Techniques in molecular biology including DNA extraction and purification, PCR and qPCR, DNA library preparation, etc.
3+ years of hands-on experience in NGS data generation with Illumina sequencers and several library preparation protocols. The ideal candidate would also have knowledge about other NGS platforms such as PacBio, Oxford Nanopore etc.
Demonstrated expertise in molecular biology wet lab skills including DNA/RNA extraction & purification from diverse tissue samples, sequencing library preparation & QC, as well as data quality QC, etc.
Extensive experience with troubleshooting and optimization of wet lab techniques to improve sequencing data quality, robustness, etc.
Expertise in the analysis and management of NGS and other big data
Individual must be authorized to work in the United States for Syngenta without work authorization sponsorship now or in the future
Visa sponsorship is not available for this position What We Offer:
Full Benefit Package (Medical, Dental & Vision) that starts the same day you do
401k plan with company match, Profit Sharing & Retirement Savings Contribution
Paid Vacation, 12 Paid Holidays, Maternity and Paternity Leave, Education Assistance, Wellness Programs, Corporate Discounts among others
A culture that promotes work/life balance, celebrates diversity and offers numerous family-oriented events throughout the year
Syngenta is an Equal Opportunity Employer and does not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
Family and Medical Leave Act (FMLA) (
Equal Employment Opportunity Commission’s (EEOC)(
Employee Polygraph Protection Act (EPPA)(

USA-North Carolina-Durham

USH-Research Triangle Park (USH)
Research Triangle Park
3054 Cornwallis Rd
Durham, 27709

USH-Research Triangle Park

Research Triangle Park

3054 Cornwallis Rd


R & D – Research