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Sr. Research Associate Protein Expression

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Company :
Corteva Agriscience

Location :
Johnston, Iowa

Expiry Date :
Sun, 06 Dec 2020 23:59:59 GMT

Apply Job :
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Description :
Description Corteva Agriscience is a leader in delivering novel and sustainable solutions for the future of agriculture. The Input Trait Discovery group combines genomic analysis, activity based screening, protein characterization and optimization to deliver novel insect control traits. We are seeking a Senior Research Associate to provide protein biochemistry expertise as part of an inter- disciplinary team for our candidate gene evaluation pipeline. Responsibilities How will you help us grow? It matters to us, and it matters to you. * Production and purification of recombinant protein from E. coli or alternative expression systems. * Conduct assays for molecular characterization of proteins. * Execute high-throughput cloning strategies for construct generation. * Perform sequence analyses and database searches using Geneious and other internal molecular biology and bioinformatics tools. * Communicate project status and initiatives with internal and external stakeholders via email and regular progress update meetings. Qualifications Requirements Educational_Qualifications Candidates should have a MS/MA in biochemistry, molecular biology, or a related discipline with 3-5 years experience, or BS/BA in biochemistry, molecular biology, or a related discipline with 8-12 years of relevant industry or academic experience. Applicable industry experience desired. Competencies_And_Qualifications * Must have demonstrated ability to design recombinant protein expression and purification strategies using E. coli or alternative expression systems such as baculovirus or yeast to generate soluble protein. Experience operating automation equipment including a colony picker or liquid handler is a plus. * Experience with molecular characterization of proteins including native size/oligomeric state determination, protein-protein interactions, and conserved domain analysis. * Must have a knowledge of molecular biology methods including DNA purification, bacterial cell culture, PCR, seamless cloning techniques, plasmid isolation and quality techniques, and DNA sequencing. * Proficiency with modern molecular biology software tools. Strong preference for individuals with expertise using Geneious software. * Excellent data management skills and a demonstrated ability to manage large, structured datasets using Excel, Access, or JMP. * Familiarity with bioinformatic sequence analysis tools like BLAST and multiple sequence alignment software. * Ability to organize, analyze, and deliver information in a concise, accurate, and professional manner. Grow your career, grow the future of agriculture, apply today. Our Campus and Community Our_Campus Our Johnston, Iowa campus is home to 2,500 employees whose mission is simple to feed the world. While our employees are busy working to solve world hunger and ensure environmental sustainability, we re taking care of them b offering convenience and comfort during the workday with an onsite fitness center, coffee shop and top-notch cafeteria touting a grill, deli, fresh salad bar and a variety of healthy menu options. Need some fresh air during your work day? Take advantage of our beautiful, tree-lined walking trails or relax by the pond. We also offer countless opportunities to connect with your colleagues through community volunteerism, parties, and holiday events. Did we mention you ll be working in state-of-the art buildings with the latest technology with colleagues from all over the world? Join us in bringing food into homes around the world, while we make you feel at home while you re at work. Our_Community Des Moines, Iowa is the fastest-growing major metropolitan area in the Midwest with a nationally ranked high quality of living. It s nicknamed the Silicon Prairie for its place as an up-and-coming hot spot for technology. Living here means Saturdays at the nationally renowned Downtown Farmers’ Market, sporting events, a robust downtown night life and access to one of the most artistic medium sized cities. If you enjoy the outdoors, Des Moines offers beautiful nature trails for a casual walking, running or biking adventures. It means going to a job you love and coming home to a community of friends and family. Communities care about their residents and residents care about their communities, making a difference for everyone who lives here. This is a place where culture flourishes and opportunities grow, where a work-life balance can be achieved, where education is unmatched, and award-winning arts and entertainment are right around the corner. Show moreShow less