Sr. Scientist I, RD

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Location :
San Diego, California

Expiry Date :
Mon, 05 Apr 2021 23:59:59 GMT

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Description :
Job Description Summary Job Description BD Biosciences, a segment of Becton, Dickinson and Company, is one of the worlds leading businesses focused on bringing innovative tools to life science researchers and clinicians. Its product lines include: flow cytometers, cell imaging systems, monoclonal antibodies, research reagents, diagnostic assays, and tools to help grow tissue and cells. Sirigen, Inc. is a subsidiary of BD Biosciences and produces fluorescent dye reagents for use in Flow Cytometry and other biological applications. We are seeking a highly motivated chemist for our dye development team to develop novel fluorescent dyes for use in Flow Cytometry. Individual will work within cross-functional teams to address unmet needs within the Sirigen dye portfolio. The ideal candidate will apply their experience with fluorescent dyes, spectroscopy, and photophysics to create dyes from early proof-of-concept to formal product development, leveraging their dye expertise to influence both small molecule and polymer designs. Job Responsibilities: – Collaborate with team to target and synthesize fluorescent dyes in line with Sirigens commercial strategy. – Develop methods for analysis and purification of raw materials, intermediates, and finished goods. – Identify innovative new technologies for fluorescence-based biological detection both as an individual contributor for your team and as a subject matter expert for the company. – Assist with development strategy by interpreting data and providing guidance to product development teams being able to speak to dye and optical changes upon aggregation, degradation, molecular design changes, etc. – Work within early product pipelines, contributing to various stages of development from early proof-of-concept to process development. – Work collaboratively in small teams with chemists, biochemists and applications scientists to establish dye specifications through statistical processes and data analysis. – Perform and oversee a wide variety of small-molecule and macromolecular synthesis, purification and characterization steps. – Draft SOPs, technical reports, and presentations for communicating project progress. – Mentor associates and scientists in experimental design, data interpretation, laboratory and instrumental techniques and best practices. – Promote a safe work environment. May provide recommendations on maintaining the safety of the work environment. Participates in Environmental Health and Safety programs. Addresses corrective actions whenever a hazard is identified. Notifies supervisor of all observed hazardous conditions or unsafe work practices. Minimum Qualifications: Education and Experience: – Minimum of a Master’s Degree with at least 5 years of organic or materials chemistry experience or Ph.D with 1-3 years of industry experience in related field. – Experience in fluorescent dye design understanding impact of functional group changes with resulting optical properties. – Experience organic synthesis/bioconjugation/materials science. – Experience with HPLC/SEC/IEX. – Experience with UV/Vis and fluorescence spectroscopy. Assets: – Understanding of concepts outside of single small molecule fluorophore, impacts to optical properties for FRET pairs or non-covalent interactions such as induced aggregate emission or ground state interactions. – Good organizational and project planning skills. – Experience with product design and product development. – Efficient with experimental design including statistical approaches such as Design of Experiment (DoE) approach. – Experience with Six Sigma, MiniTab, or statistical analysis. – Able to present clear and concise written and oral communications to colleagues and supervisors. – Lead and/or participate in technical meetings and provide recommendations based on technical results. – Strong diagnostic, analytical and technical ability. – Strong technical writing skills. – Multi-task to cover a variety of job functions. – Comfortable working in a fast-paced environment. Becton, Dickinson and Company is an Equal Opportunity/Affirmative Action Employer. We do not unlawfully discriminate on the basis of race, color, religion, age, sex, creed, national origin, ancestry, citizenship status, marital or domestic or civil union status, familial status, affectional or sexual orientation, gender identity or expression, genetics, disability, military eligibility or veteran status. #LI-PRO Primary Work LocationUSA CA – San Diego (BDB) Additional Locations Work Shift