Scientist

Company : Genesis10

ApTask Global Workforce (AGW) is currently seeking a Scientist –  Onsite for a position located in Pleasanton, CA. This is an 12+ month contract opportunity.

About Client:
The Client is known for its groundbreaking work in genetic engineering and biopharmaceuticals. It was the first company to successfully produce a recombinant version of human insulin, which revolutionized the treatment of diabetes. Since then, it has developed numerous other important biotech drugs, particularly in the fields of oncology (cancer treatment) and immunology.

Job Description:

• Pathology Biology & Integrated Analytics group (Pleasanton, CA) at Roche Diagnostics is seeking a highly
• motivated Scientist for molecular cloning, cell culture, FPLC purification and antibody engineering and characterization.
• The qualified candidate will join a team of scientists focused on monoclonal antibody development for IVD and CDx assay.
• This position will be actively participating in antibody development, engineering, production and characterization.
• Job function requires the ability to evaluate, summarize and report study results, make independent decision and collaborate with teams at multiple sites.

Responsibilities:

• Plans and/or manages smaller, less complex local projects (e.g. with moderate project management complexity, problem definition, and/or short to medium term implications).
• Participates in project teams across the R&D department and functional groups
• Can represent the Team Lead in project teams in his/her absence on instruction
• Ensures that quality standards are met and plans and coordinates the performance of tasks largely independently.
• Is aware of new developments in the field and refers to the possible use of these in diagnostics.
• Contributes to collaboration and close networking within the departments as part of R&D projects.
• Analyzes and interprets the R&D results largely independently and presents them to the relevant committees within their own function.
• Uses specified strategies to resolve problems and acts within defined guidelines.

Soft skills:

• Strong work ethic and collaborative attitude.
• Proven capacity to work effectively and positively in a small, tight-knit team, supporting colleagues and contributing to a shared goal.
• Strong analytical skills to interpret complex experimental results and troubleshoot unexpected technical challenges.
• Proactive approach to identifying potential project roadblocks and proposing solutions.
• Excellent communication and leadership skills with a deep commitment to working as part of teams and recognizing the strengths of everyone on the team.
• Ability to clearly and concisely present complex data (written and verbal) to both scientific and non-scientific team members.
• Ability to efficiently manage multiple tasks and pivot priorities as research needs evolve.
• Demonstrates self-motivation and the initiative to drive the project forward independently.
• Excellent organizational skills to manage laboratory resources, schedules, and deadlines effectively to ensure key milestones are met.

Hard skills (Core Requirements):

• Demonstrated experience with the end-to-end antibody development process, from molecular cloning through expression, purification, and biochemical/functional characterization.
• Advanced proficiency in standard molecular cloning techniques (e.g., PCR, restriction/ligation, Gibson assembly) for subcloning antibody sequences into mammalian expression vectors.
• Strong hands-on experience analyzing and manipulating antibody sequences, with a deep understanding of antibody architecture (VH/VL, CDRs, frameworks) and routine use of sequence analysis tools to support antibody engineering.
• Hands-on experience expressing antibodies in mammalian systems (e.g., HEK293, CHO).
• Demonstrated experience in antibody purification and characterization, including protein A/G–based purification (e.g., FPLC) and downstream analytical methods such as ELISA, SDS-PAGE, WB, HPLC and IHC.

Is a Plus:

• Experience with laboratory automation and workflow optimization (e.g., automating cloning, expression, purification, or analytical assays).
• Ability to interpret structural data (PDB files) and relate it directly to experimental outcomes (e.g., binding, stability).
• Knowledge of biophysical characterization techniques (eg. DSC, DLS) to assess protein structural integrity and stability.
• Experience with computational protein engineering and antibody epitope modeling.
• Experience with advanced protein modifications analysis and their impact on function.
• Familiarity with formulation and stability studies for final antibody products.

Hard skills:

• Experience and in-depth knowledge in monoclonal antibody development and antibody engineering.
• Proficiency in standard cloning techniques (e.g., PCR, restriction/ligation, Gibson assembly) for subcloning antibody sequences into mammalian expression vectors.
• Familiarity with antibody sequences and sequence analysis software.
• Significant experience with transient protein expression in mammalian cell culture systems (e.g., HEK293, CHO).
• Experience with antibody purification and characterization (eg. FPLC purification, HPLC, ELISA, SDS-PAGE, WB, IHC).
• Domain knowledge in oncology, immunology, or protein chemistry.
• MSc. but years of relevant experience is most important 5-10 years hands on exp.

Pay Rate Range: $53.60-$91.26/Hr

If you have the described qualifications and are interested in this exciting opportunity, apply today!

Aptask Global Workforce (AGW)
ApTask Global Workforce (AGW) is a certified Minority and Veteran workforce solutions company. AGW delivers operational, clinical, lab and professional talent with a strong focus on healthcare and life sciences. The company supports clients with reliable staffing, program expertise and a commitment to quality, speed and consistent delivery.

Benefits of working with ApTask Global Workforce include:

• Medical
• Dental
• Vision
• Sick Pay (for applicable states/municipalities)

Our team stays close to the process and is here to guide you every step of the way. To learn more, please visit our website (url removed) .

ApTask Global Workforce is an Equal Opportunity Employer. Candidates will receive consideration without regard to their race, color, religion, sex, sexual orientation, gender identity, national origin, disability or status as a protected veteran.

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