Website Mindlance
Mindlance
Company : Mindlance
Job Description:
The Reverse Translation Genomics Scientist sits within the Genomic Technologies (GTECH) organization of the Genomics Research Center (GRC) and is designed for a scientist capable of independently executing experimental workloads, troubleshooting complex laboratory challenges, and interpreting genomic data to support translational and discovery research. This scientist will support the Reverse Translation initiatives by generating high quality genotyping data sets using microarray based platforms.
The successful candidate will operate with a high degree of scientific autonomy and drive experiments end to end while partnering closely with GRC scientists, bioinformatics collaborators, and therapeutic area stakeholders to deliver robust, decision enabling data sets.
Key Responsibilities
Genomic Data Generation, Data Quality & Scientific Interpretation
Independently plan, execute, troubleshoot, and deliver high throughput genomic workflows to produce high quality genotyping data sets that support reverse translation, biomarker, and or discovery/development programs
Drive validated end to end genotyping workflows utilizing microarray platforms, from experimental setup through data handoff within expected timelines
Independently operate, maintain, and troubleshoot microarray and liquid handling platforms to ensure consistent data quality, robustness, and throughput
Accountable for data quality by independently performing QC, identifying root causes of failures, and implementing corrective and/or preventive actions
Apply scientific judgment to recommend follow up experiments, assay adjustments, or alternative approaches
Accurately document experimental design, execution, troubleshooting, and outcomes in accordance with laboratory and data governance standards
Prepare clear written summaries and reports, and present data, interpretations, conclusions, and recommendations to technical, project, or senior leadership stakeholders
Operations, Compliance & Continuous Improvement
Maintain reagent inventory and coordinate with management to ensure uninterrupted experimental execution
Basic Qualifications
Bachelor s degree in Genetics, Genomics, Molecular Biology, or a related field with typically 2+ years of relevant experience, or
Master s degree in Genetics/Genomics or a related field with 2+ hands on laboratory experience
Demonstrated ability to independently execute and troubleshoot genomic laboratory workflows
Proven experience generating and assessing quality metrics of genomic data sets
Strong working knowledge of genetics and genomics principles
High attention to detail with strong data ownership mindset
Experience operating and troubleshooting high throughput and automated laboratory workflows
Adhere to established SOPs and independently contribute to the development, revision, and continuous improvement of laboratory procedures
Contribute to the evaluation, development, and validation of innovative technologies aligned with reverse translation and GTECH or organizational strategic priorities
Preferred Qualifications
Experience generating genotyping data using microarray platforms and performing data QC
Experience with NGS library preparation, sequencing, and primary data QC
Experience with nucleic acid QC, sample tracking, and LIMS
Prior experience in a high throughput industry or centralized genomics core laboratory environment
Key Competencies
Scientific independence in execution, troubleshooting, and data interpretation
Strong organizational, prioritization, and communication skills
Ability to interpret data critically and translate findings into actionable insights
Demonstrated experimental rigor and continuous improvement mindset
Comfortable operating autonomously while collaborating effectively in matrixed teams
Ability to thrive in a dynamic, fast paced research environment