Website Integrated Resources, Inc
Integrated Resources, Inc
Company : Integrated Resources, Inc
Job Title: Scientist I
Job Location: Framingham, MA
Job Duration: 12 Months+ Possible Extension
Pay Range: $55 – $60/hr. on w2
Manager Notes:
- PhD with 0-2 years of relevant experience in Biology, Cellular Biology, Molecular Biology
- Master's Degree /Bachelor’s Degree with equivalent industry experience.
Top 3 Required skills:
- Minimum 1-year experience
- Cell Culture Tissue Culture Exp/ Mammalian cell culturing – sterile technique, cell counting, passaging, cryopreservation, etc.
- Ability to work in a team environment and follow established protocols where available.
Nice to Have Skills:
- Runway, mammalian expression lab experience
- Mammalian CHO (big bonus to have CHO cell experience!)
- Soft skills, good communication, Notebooks
- Gibson assembly, gene editing, CRISPR
Job Responsibilities/Department Description:
- We are seeking a highly motivated individual with a strong background in mammalian cell culture to support research and innovation within our Cell Line Development expression platform.
- The research focus will center on improving components, methodologies, and platforms used in generating recombinant CHO cell lines expressing complex biologics.
Position Overview/Key Responsibilities
- Candidates highly experienced in cellular and/or molecular biology are encouraged to apply. Prior experience in CHO cell biology is highly desired.
- Design, execute and analyze platform research studies to support process development activities which aim to reduce overall timelines while improving cell line productivity and product quality.
- Assist in generation of engineered mammalian cell lines (transfection pools, clones) expressing candidate biotherapeutics.
- Assist in several studies simultaneously to optimize cell line generation processes.
- Perform mammalian cell culture techniques: sterile technique, cell counting, passaging, cryopreservation, etc.
- Perform basic molecular biology techniques: DNA plasmid preparation, PCR, restriction enzyme digestion, etc.
- Self-motivated with excellent attention to detail and superb organizational skills, having a proven ability to work in a highly collaborative environment and communicate transversally.
- Flexibility, adjusting to a fast-paced, goal-oriented environment and willingness to expand and broaden one’s skillset.
- Prepare reports, presentations, and data sets to effectively communicate results, progress and plans.
Basic Qualifications:
- PhD with 0-2 years of relevant experience in Biology, Cellular Biology, Molecular Biology or Master's Degree /Bachelor’s Degree with equivalent industry experience.
Preferred Qualifications:
- Experience in suspension culture of CHO cell lines in a pharmaceutical or biotechnology setting.
- Experience and knowledge of molecular techniques including gene editing, copy number analysis, Gibson assembly etc.