USA-Scientist III (Scientific)
Expiry Date :
Thu, 05 Nov 2020 23:59:59 GMT
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Title: Scientist III
Location: Cambridge, MA
Duration: 12+ months
The Proteomics group is seeking an enthusiastic scientist who will be involved in the discovery of Client therapeutics. The scientist will contribute to interdisciplinary project teams by developing and implementing innovative proteomic methods (not related to mass spectrometry) for identification of pharmacodynamic (PD) biomarkers, elucidation of mechanisms of action, and characterization of complex biotherapeutics. In this position, the scientist will also be responsible for evaluating and employing of the emerging cutting-edge proteomic technologies, as well as maintaining operational readiness of the equipment and resolving analytical challenges in a timely fashion. The term of the position might be extended.
Extensive experience in protein biomarker research – design, validation and implementation of custom protein immunoassays (Simoa, MSD, Luminex, ELISA, Simple Western), preparation of tumor, tissue, and blood samples for analysis;
good knowledge of protein characterization methods (CE-SDS/cIEF, HPLC with SEC/MALS, DLS);
experience with lab automation (Biomek, CyBio, Formulatrix liquid handling workstations, plate washers, etc.);
good knowledge of scientific data analysis, graphing and curve fitting software (Excel, GraphPad Prism, TIBCO Spotfire);
experience in oncology and immunology research is a plus;
experience in enzymology research is a plus;
strong organizational and analytical skills, attention to details;
ability to write technical reports describing experiments and their outcome.
Master’s degree in Biochemistry, Biology, Molecular biology, or related disciplines with 10 years of experience or bachelor’s degree with very significant experience in the field.