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Masks mandates have major impact, study finds

The research described in this article has been published as a working paper but has not yet been peer-reviewed by experts in the field.

Masks reduce the spread of Covid-19. But just how much of an effect do they have? A study co-authored by an MIT professor finds that if the U.S. had introduced a uniform national mask mandate for employees of public-facing businesses on April 1, the number of deaths in the U.S. would likely have been 40 percent lower on June 1.

NEW MOLECULE REVERSES ALZHEIMER’S-LIKE MEMORY DECLINE

A drug candidate developed by Salk researchers, and previously shown to slow aging in brain cells, successfully reversed memory loss in a mouse model of inherited Alzheimer’s disease. The new research, published online in July 2020 in the journal Redox Biology, also revealed that the drug, CMS121, works by changing how brain cells metabolize fatty molecules known as lipids.

COVID-19 CAUSES ‘HYPERACTIVITY’ IN BLOOD-CLOTTING CELLS

Changes in blood platelets triggered by COVID-19 could contribute to the onset of heart attacks, strokes, and other serious complications in some patients who have the disease, according to University of Utah Health scientists. The researchers found that inflammatory proteins produced during infection significantly alter the function of platelets, making them “hyperactive” and more prone to form dangerous and potentially deadly blood clots.

CLUES TO COVID-19 COMPLICATIONS COME FROM NET-LIKE INFLAMMATORY RESPONSE

An overactive defense response may lead to increased blood clotting, disease severity, and death from COVID-19. A phenomenon called NETosis—in which infection-fighting cells emit a web-like substance to trap invading viruses—is part of an immune response that becomes increasingly hyperactive in people on ventilators and people who die from the disease.