Scientist II

Company : Tucker Parker Smith Group (TPS Group)

Country: United States

Location : San Rafael, California

Post: Fri, 24 Mar 2023 06:32:31 GMT

Expires: Fri, 21 Apr 2023 23:59:59 GMT

Apply Job : Apply Online

—————————— Job Description ——————————

Scientist II- Cell Biology for Hematology

Location: San Rafael, CA. (Lab-based Role On-Site)

DIRECT HIRE

Pay Rate: $112-$150k DOE

On behalf of our leading pharmaceutical client, we are seeking for a cell biologist with experience in hematologic disorders who will conceive strategies, lead development, evaluation and implementation of state-of-the-art cell-based models to identify therapeutic interventions, in support of preclinical proof-of-concept and mechanisms of actions investigations of Client therapeutics for non-malignant blood disorders.

Duties:

Provide scientific and intellectual input to guide project-related cell biology proof-of-concept and investigative efforts within the context of interdisciplinary project teams.

Initiate, direct and execute the development, optimization, qualification of robust cell-based assays.

Analyze data with applicable bioinformatics tools/scientifically sound interpretation and present data at group/departmental meetings.

Able to troubleshoot experiments based on thorough understanding of assay principles.

Author technical reports and SOPs associated with the cellular and molecular assays developed and qualified.

Work with junior research associates and scientists on experimental design, troubleshooting, assay optimization and data interpretation, if applicable.

Participate in exploratory studies driving the evaluation of state-of-the-art new technology platforms, and innovative upgrades for existing assay platforms.

Identify, develop, and maintain relationships with contract research organizations to maximize group productivity and assure inclusion of latest scientific thinking and guidelines in the research plan.

Contribute to the peer review process, both internally and externally, to help assure the company’s translational research is conducted at the highest level of quality, integrating business and development objectives.

Education & Experience:

Ph.D. in Cell Biology, Genetics, Hematology, or a related field with postdoctoral and at least 2+ years of industry experience are required. Or equivalent 2-5+ years in industry.

Demonstrated experience in tissue culture with iPCS, primary cells (e.g., hepatocytes) and human hematopoietic cells.

Proficiency with flow cytometry including designing and optimizing multi-parameter flow cytometry panels.

Proficiency in developing and optimizing high-content imaging bioassays independently with limited guidance a plus.

Experience with confocal microscopy and live-cell imaging.

Proficiency in various molecular biology analytical methods (qPCR or ddPCR), and other standard molecular biology techniques.

Background in viral and non-viral gene therapy, cellular or molecular biology is a plus.

Experience with analytical and/or statistical software (e.g., JMP, Softmax Pro, XLfit, Gen5 etc.), is highly beneficial.

Please submit your resume in Word or PDF format to be considered.