Website Integrated Resources, Inc
Integrated Resources, Inc
Company : Integrated Resources, Inc
Job Title: Senior Associate Scientist
Job Location: Cambridge, MA 02142
Job Duration: 8 months+
Shift: Standard
Payrate: $40-$46/ hr on W2
Skill set – Antibody analytical development experience., Analytical HPLC/LCMS/UV-vis
Justification: Summary of Key Responsibilities
- Hands-on lab support and process development for the chemical synthesis and downstream processing of oligonucleotide-based drug substance
- Synthesis of oligonucleotides up to 11 mmol scale
- Downstream processing of oligonucleotides including prep-HPLC, Ultrafiltration, annealing, concentration and Lyophilization
- In process analytical testing including AX-HPLC, IPRP-HPLC, LCMS, UV-vis
- Technical support for optimization of contract manufacturing processes
Qualifications:
- BS in Chemistry with 3+ years lab experience, preferably in an industrial setting.
- Basic understanding of analytical techniques (pH, osmolality, conductivity measurement, HPLC, LC-MS etc.). Related hands-on experience is preferred. Knowledge of oligonucleotide manufacture process including phosphoramidite chemistry, chromatography, ultrafiltration etc. is a plus.
- Experience in record-keeping and excellent laboratory documentation practice, are required. Strong commitment to high laboratory and scientific standard; ability to maintain a safe, clean, and orderly laboratory work environment; assist in routine lab and equipment maintenance.
- Good communication skills are a must for this position. The successful candidate must be a responsible and proactive individual who is able to work as a team player in a highly dynamic environment with aggressive timelines.
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